Effects of Treatment Combining 9300 nm Carbon Dioxide Lasers and Fluoride on Prevention of Enamel Caries: A Systematic Review and Meta-Analysis

The objective of this study is to conduct a systematic review the literatures on effect treatment combining 9300 nm carbon dioxide (CO2) lasers and fluoride prevention enamel caries. A literature search was performed using PubMed, Scopus, Web Science. keywords were ((9300 nm) OR (9.3 µm) (carbon laser) lasers) (CO2 lasers)) AND ((fluoride) (fluorides)) ((dental caries) (caries) (remineralization) (demineralization) (demineralization)). Meta-analysis compare change in mineral content by laser irradiation (F + L) with that (F) (L). identified 946 potential publications five laboratory studies chemical model for cariogenic challenge determining loss included review. comparing F L showed standard mean difference −1.58 (CI: −2.13, −1.03). −1.84 −2.30, −1.39), low heterogeneity (I2 = 49%, p 0.04). In conclusion, better than preventing demineralization.